MOVEMENT DISORDERS

Reports on TV 

Radio Canada Deep brain stimulation for Parkinson's disease (8 contact lead) - Dr Michel Prud'Homme

TVA Deep brain stimulation for Parkinson's disease (8 contact lead) - Dr Michel Prud'Homme

The pedunculopontine nucleus as a target for deep brain stimulation. Hamani C, Moro E, Lozano AM. Journal of Neural Transmission, 2011 Oct;118(10):1461-8. Epub 2010 Dec 31.
The authors review several aspects of the pedunculopontine nucleus (PPN) as a target for deep brain stimulation in patients with Parkinson’s disease. They also review the outcome of recently published clinical trials.  Link to PubMed.

Unilateral subdural motor cortex stimulation improves essential tremor but not Parkinson's disease. Moro E, Schwalb JM, Piboolnurak P, Poon YY, Hamani C, Hung SW, Arenovich T, Lang AE, Chen R, Lozano AM. Brain. 2011 Jul;134(Pt 7):2096-105. Epub 2011 Jun 6.
The authors studied the efficacy and safety of unilateral subdural motor cortex stimulation in 5 patients with Parkinson’s (PD) and 6 with Essential Tremor (ET). They found that MCS was useful in the treatment of contralateral hand tremor for the ET patients but it was not effective for the parkinsonian signs in the PD group.  Link to PubMed.

Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues. Bronstein JM, Tagliati M, Alterman RL, Lozano AM, Volkmann J, Stefani A, Horak FB, Okun MS, Foote KD, Krack P, Pahwa R, Henderson JM, Hariz MI, Bakay RA, Rezai A, Marks WJ Jr, Moro E, Vitek JL, Weaver FM, Gross RE, DeLong MR. Archives of Neurology, 2011 Feb;68(2):165. Epub 2010 Oct 11.
The authors provide recommendations to physicians, health care providers and patients on several issues relating to deep brain stimulation for Parkinson’s disease. Link to PubMed.

Unilateral pedunculopontine stimulation improves falls in Parkinson's disease. Moro E, Hamani C, Poon YY, Al-Khairallah T, Dostrovsky JO, Hutchison WD, Lozano AM. Brain, 2010 Jan;133(Pt 1):215-24. Epub 2009 Oct 21.
In a double-blind evaluation of unilateral pedunculopontine nucleus (PPN) deep brain stimulation in 6 patients with Parkinson’s, the authors found a significant reduction in falls at 3 and 12 months post-operative. Link to PubMed.

UROLOGY

Long-Term Outcome and Surgical Interventions After Sacral Neuromodulation Implant for Lower Urinary Tract Symptoms: 14-Year Experience at 1 Center. Ali A. Al-zahrani, Ehab A. Elzayat and Jerzy B. Gajewski. The Journal of Urology, Vol. 185, 981-986, March 2011.
Outcomes and reasons for re-operation following InterStim(R) sacral neuromodulation implants for patients with lower urinary tract dysfunction, are reported in 96 cases over a 14 year period. The authors conclude that this therapy provides good long term outcomes, with an average success rate of 81.7%. Link to PubMed.

PAIN

Report on CTV

Chronic pain treatment by spinal cord stimulation - Dr Mohammed Shamji

Occipital Nerve Stimulation for Intractable Occipital Neuralgia: An Open Surgical Technique. Philippe Magown, Rene Garcia, Ian Beauprie and Ivar M. Mendez. Clinical Neurosurgery,Vol.56, 2009.
The authors describe an open surgical technique which ensures optimum and secure placement of a lead to treat intractable occipital neuralgia. Outcomes are reported on 7 patients with excellent pain control quantified as a 97% reduction in pain on the Visual Analog Scale. Link to PubMed.